Graduate Students

Robert Hale's picture

Robert was born in New York City and grew up in Astoria, NY, and Little Silver, NJ. As an undergraduate engineering major at the Stevens Institute of Technology, he found that he was doing more problem solving under the direction of mass spectrometry specialist Dr. Athula Attygalle than in any engineering class. As a result, he changed his major to chemistry upon beginning his sophomore year. He performed mass spectrometric studies of oxalate and carbonate salts for his undergraduate research before earning a B. S. in chemistry in May 2015. He is enjoying gaining experience in the more tactile, sensory world of organic synthesis as he works to extend the methodology developed for glucosepane to access other natural products. When outside of the lab, Robert enjoys cooking, active things, the occasional trip to the shooting range and discussing all manner of history and politics, especially that to do with the railroads, cities and infrastructure. 

Jason Ray's picture

Jason grew up in North Carolina and decided at age ten to become a scientist. He studied chemistry at Brigham Young University, where his coursework focused on organic chemistry and biochemistry. He did research with Dr. Jeffery Tessem on genetic pathways that could be targeted to reverse type 1 and type 2 diabetes. He was a teaching assistant for several general chemistry classes and tutored students extensively in both math and chemistry. Because of his love for research and teaching, Jason plans to become a professor at a primarily undergraduate institution. His research in the Spiegel lab focuses on novel uses of bifunctional molecules. Outside of lab, Jason enjoys reading, running, and spending time with his wife.

Rebecca Howell's picture

Rebecca grew up in Connecticut and attended Bucknell University where she majored in Cell Biology/ Biochemistry.  At Bucknell, she worked in Dr. Charles Clapp’s laboratory using site-directed mutagenesis to probe conformational changes of soybean lipoxygenase.  After graduation, she completed a one-year appointment in the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center in Dr. Joern Schmitz’s laboratory.  Here she generated stable cell lines expressing soluble and membrane bound Fc receptors to explore differences in therapeutic antibody binding in Rhesus macaques and humans. Next, she joined the Immunology team at Moderna Therapeutics and worked under the guidance of Dr. Gilles Besin for three years developing high-throughput flow cytometry-based screening methods to assess biological interactions of novel delivery and mRNA chemistries.  Her work on the Moderna platform contributed to several drug candidates currently in Phase I.  She began her graduate studies at Yale in Chemical Biology in 2018 and joined the Spiegel lab to work at the interface between chemistry and immunology. In her free time, Rebecca enjoys baking, cooking, traveling with her husband and playing with her dog.

Edward deRamon's picture

Eddie grew up in New York where he attended SUNY New Paltz, majoring in Chemistry. There, his research was primarily focused in organic chemistry, while a summer research program at Johns Hopkins University opened him up to chemical biology. He began his PhD in Chemical Biology at Yale in 2018, where his combined interest in these research areas led him to join the Spiegel lab. Here, his work is primarily focused on the development of therapeutically relevant bifunctional molecules. Outside of lab, Eddie enjoys hiking, camping, and weightlifting.